7-OH vs. classic kratom

01/08/2025

We all know kratom and for some it is already becoming a classic. But have you heard about the newer derivative 7-OH? How do 7-OH and classic kratom differ and which one is better? Let's figure it out together.

What is classic kratom?

Before we get to the individual differences between these substances, let's get acquainted again with kratom. Classic kratom comes from the leaves of the Mitragyna speciosa tree, which grows mainly in Southeast Asia. The leaves contain alkaloids, primarily mitragynine and 7-hydroxymitragynine (7-OH), which affect our body and mind.

Classic kratom is usually sold as dried powder or capsules. Depending on the dose and strain, it can have stimulating or sedative effects.

At lower doses it often stimulates, increases focus and energy.
At higher doses it can act as a mild analgesic or help to relieve tension.

What is 7-OH?

7-OH is actually a substance that naturally occurs in classic kratom but in a much smaller amount. It is 7-hydroxymitragynine, an alkaloid that has stronger effects than mitragynine, which is the main alkaloid in kratom.

Recently, products labeled as 7-OH have started to appear, meaning they have been processed to contain a higher concentration of this substance. These are often special extracts or isolates that have stronger and faster onset of effect.

Main differences between 7-OH and classic kratom

1. Strength of effect

7-OH is much stronger because 7-hydroxymitragynine binds to opioid receptors in the body much more effectively than mitragynine. This means that even a smaller dose of 7-OH can produce a stronger effect, especially regarding analgesic and relaxing effects.

2. Onset and duration

Classic kratom usually starts to work within 30 to 60 minutes and effects may last 3 to 6 hours. 7-OH kratom often acts faster and can have more intense, but also shorter duration of effect.

3. Safety and tolerance

Because 7-OH is stronger, it needs to be handled more carefully. Higher concentrations of this substance can increase the risk of side effects, such as dizziness, nausea, or even dependence if used frequently and in large doses. Classic kratom is generally considered safer for regular use, but of course, proper dosing rules still apply.

4. Legality and availability

In many countries, classic kratom is legal and commonly available. Special extracts with higher 7-OH content may already be regulated more strictly due to their potency. Therefore, 7-OH may not be available everywhere or may require more caution.

When to choose classic kratom and when 7-OH?

If you are a beginner or looking for milder and balanced effects, then classic kratom is definitely a better choice. It will provide you with energy, mood improvement, or pain relief without too strong a “hit.” Moreover, its effects are slower and longer-lasting, which is suitable for longer-term use.

On the other hand, if you have experience, are looking for quick and strong relief from severe pain or want more intense relaxation, it may be interesting to try 7-OH. But you should always start with a very low dose and observe how your body reacts.

What to watch out for?

The basic rules apply to both types of kratom:

Do not combine kratom with alcohol or other medications without consulting a doctor.
Do not exceed the recommended dosage – especially with 7-OH!
Avoid long-term daily use to prevent dependence.
If you are pregnant, breastfeeding, or have health issues, it is better to avoid using kratom.