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Trans-resveratrol is a natural antioxidant that has gained attention for its potential positive effects on health. Although it is a plant-based substance, it can also have side effects, especially when taken in higher doses or over a long period. Let's discuss what to watch out for.
What is trans-resveratrol?
Trans-resveratrol is a natural plant compound belonging to the group of polyphenols, acting as a very strong antioxidant. To summarize its positive effects, it is most known for its protective effects on cells, anti-inflammatory properties, and potential impact on longevity.
In the body, it helps neutralize free radicals that cause cell damage and aging. Unlike regular resveratrol, trans-resveratrol is a more stable and bioavailable form of this substance.
Where can it be found:
- Red grapes and grape skins
- Red wine (it is most abundant in dry red wine)
- Blueberries
- Mulberries
- Peanut skins
- Supplements labeled as Trans-resveratrol
If you want to know more about this substance, check out our detailed article: What is Trans-resveratrol and why does it have such interesting effects?
Side effects of Trans-resveratrol
In the previous article, we discussed the positive impact of trans-resveratrol on health, but now we will focus on the potential side effects and what to watch out for.
1. Digestive issues
The most common side effects include digestive problems, such as:
- nausea
- bloating
- diarrhea
- stomach pain
These issues typically occur at higher daily doses.
2. Drug interactions
Trans-resveratrol can affect the effectiveness of certain medications, particularly:
- Anticoagulant drugs (blood thinners) – its anti-clotting properties may increase the risk of bleeding when combined with these medications.
- Medications for blood pressure and cardiovascular problems – it can affect their effectiveness, so it is important to consult a doctor before using it.
3. Hormonal effects
Since it belongs to the group of phytoestrogens, substances that mimic female hormones, at higher doses, it can:
- slightly affect hormonal balance
- disrupt the menstrual cycle
- affect hormone levels in men
In standard supplements, this effect is minimal.
4. Allergic reactions
In rare cases, it may cause an allergic reaction, which can manifest as:
- itching
- rash
- breathing difficulties
If this happens, it is recommended to stop use immediately and consult a doctor.
Although Trans-resveratrol is a natural substance with numerous health benefits, like other active substances, it can have side effects, especially at higher doses or with prolonged use.
How about dosage?
Resveratrol from regular diet or wine does not overload the body, but higher doses come from supplements. It is well absorbed and metabolizes quickly, and the safe daily dose for adults is around 450 mg. Doses above 1g may cause diarrhea, bloating, or stomach pain. At the recommended amount, side effects are generally not observed. Repetition is the mother of wisdom, and caution is especially necessary when taking certain medications, where it is best to consult a doctor beforehand.
Summary
Trans-resveratrol is a natural antioxidant with great potential for health, but like other bioactive substances, it can have its side effects. The most common are:
- digestive issues
- drug interactions
- hormonal effects
- rare allergic reactions
If you want to try it, start with a lower dose and monitor how your body reacts. And if you take medications or have health issues, it is recommended to consult a doctor before starting.