Who should avoid Berberine and Spermidine?

Although both of the supplements you see above have enormous potential, they are not the right choice for everyone. And that is exactly what we would like to focus on before automatically adding them to our daily routine. So, let's talk about who should seriously consider their use, or rather avoid it.

What do berberine and spermidine have in common?

Before we dive into the risks and warnings of what to watch out for, let's introduce these substances. Although they are two completely different substances, they do share something in common. Berberine is a natural alkaloid of plant origin, while spermidine is an organic compound naturally found in the human body. So, what connects them?

• Longevity: Both substances are associated with a positive impact on life energy and longevity. They help keep the body in better condition, slow down cellular aging, and protect cells from damage.

• Cell protection and regeneration: Both substances contribute to supporting proper metabolism, although each does so through different mechanisms. Berberine regulates blood sugar and fat levels, while spermidine helps optimize cellular processes.

• Growing popularity in the health and nutrition world: Yes, this is something berberine and spermidine have in common. In recent years, they have become the subject of many studies, articles, and discussions due to their potential to improve the quality of life.

• Natural origin and safety when properly dosed: Perhaps we are jumping ahead, but it is a fact that they are naturally present in some foods or herbs, and their supplementation is safe when recommended doses are followed.

However, sometimes things can go awry, and some people should reconsider using these substances. Why, and who are they?

When to be cautious with Berberine

As we already mentioned, berberine is a natural alkaloid with proven effects on metabolism, blood sugar levels, digestion, and heart health. You can read more about it in our article Berberine: Natural Support for Metabolism and Health.

But beware, its use can be risky for certain groups:

1. Pregnant and breastfeeding women:Berberine can affect uterine activity and the transfer of substances into breast milk. It is therefore better to avoid it during this time.

2. People taking diabetes medications:Because berberine significantly lowers blood glucose levels, combining it with anti-diabetic drugs could lead to dangerous hypoglycemia.

3. People with low blood pressure:Berberine can further lower blood pressure, which may result in dizziness, fatigue, or weakness.

4. People on blood thinners or antibiotics:Berberine can interfere with their effects and cause unexpected interactions.

5. Children:The safety of berberine in children has not been sufficiently studied, so it is not recommended for use.

When to be cautious with Spermidine

Spermidine is a substance that our body can naturally produce itself to a certain extent, but its levels decrease with age. Supplements containing spermidine are associated with supporting cell regeneration, rejuvenating the body, and even protecting against diseases.

Want to know more? Check out our article Spermidine: The Key to Longevity and Cellular Regeneration.

But when is it better to consult a doctor before using it, or to avoid it altogether?

• Pregnant and breastfeeding women:Just like with berberine, there are not enough studies to confirm its safety during pregnancy and breastfeeding.

• Cancer patients:Since spermidine promotes cell growth and division, it could pose a risk for certain tumors. If you are undergoing cancer treatment, always consult with a professional first.

• People with allergies to supplement ingredients:If you are sensitive to certain natural extracts or added substances, always carefully check the ingredients list.

Both berberine and spermidine are fascinating substances with huge potential. They can benefit metabolism, cells, and overall health, but not every body is ready for their effects. If you fall into one of the mentioned groups, it's definitely a good idea to consult a doctor or consider a gentler approach.